This database provides comprehensive cancer incidence data, crude rates, and age-adjusted rates.  Crude rates indicate the number of cases reported each calendar year per 100,000 population.  Age-adjusted rates are weighted averages of the age-specific (crude) rates, where the weights are the proportions of persons in the corresponding age groups of a standard million population.  It includes all cancers reported by the Centers for Disease Control and Prevention. See CDC for more details.

• Data are not available from 1999-2009 for Connecticut, Hawaii, Iowa, New Mexico, and Utah.
• Additionally, data are missing for some states in some years: Alabama (1999), Arkansas (1999, 2000, 2002), District of Columbia (2002, 2008), Maryland (2001), Mississippi (1999-2002), Nevada (1999, 2007), North Carolina (1999-2000), South Dakota (1999-2000), Tennessee (1999-2003), and Virginia (1999-2002, 2008).  
• Population estimates have been modified and are based on the annual time series of population estimates produced by the Population Estimates Program of the U.S. Bureau of the Census. 
• Prior to 2012, the category All Invasive Cancer Sites Combined was known as All Cancer Sites Combined.